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Video Endoscopic Sequence 1 of 7.
Pedicled Polyp of the Descending Colon.
This is the case of a 54 year-old male with rectal bleeding.
For more endoscopic features download the video clip by clicking on the endoscopic image if you would like to appreciate in full screen, wait to be downloaded the video complete then press Alt and Enter. All endoscopic images shown in this Atlas contains video clips.
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Video Endoscopic Sequence 2 of 7.
Tubular Adenoma on a Long Stalk.
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Video Endoscopic Sequence 3 of 7.
Adenomatous polyps are precursors of most colorectal cancers, and their prevalence increases with age. The chance of detecting adenomatous polyps at colonoscopy is generally independent of the indication for the procedure.
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Video Endoscopic Sequence 4 of 7.
Endoscopic snare excision of large pediculated polyp.
Most pedunculated polyps are removed by transection of the stalk with a polypectomy snare. The major risk with this approach is postpolypectomy bleeding. As a result, many endoscopists use one or more methods to reduce the risk of bleeding, particularly in polyps with wide stalks (pedicles larger than 1 to 1.5 cm in diameter).
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Video Endoscopic Sequence 5 of 7.
The practice of removing polyps at colonoscopy is based on the assumption that their removal prevents progression to cancer. This concept, often called the adenoma-carcinoma sequence.
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Video Endoscopic Sequence 6 of 7.
Large pedunculated polyps (> 2-3 cm) are often easily removed with standard snare cautery techniques. The difficulty most commonly encountered is when a large polyp has a particularly long stalk, and the head of the polyp prolapses in both directions when snaring is attempted.
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Video Endoscopic Sequence 7 of 7.
Final Status of the Polypectomy.
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Video Endoscopic Sequence 1 of 13.
A 59 year-old female that underwent a colonoscopy due to medical control of routine, the image displays a sessile Tubulovillous adenoma that emerging from the ileocecal valve.
Medline.
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Video Endoscopic Sequence 2 of 13.
An adenoma was located at the level of the digestive mucosa. It is a benign tumor, always dysplastic and considered as a pre-cancerous lesion.
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Video Endoscopic Sequence 3 of 13.
The image and the video display the catheter spraying the methylene blue.
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Video Endoscopic Sequence 4 of 13.
Chromoendoscopy.
For more endoscopic features download the video clip by clicking on the image.
Medline.
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Video Endoscopic Sequence 5 of 13.
Using high-magnification chromoscopic colonoscopy.
Tubulovillous adenoma, Video-endoscopy with chromoscopy. Magnifying endoscopy with methylene blue demonstrates sulciform pattern.
Medline.
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Video Endoscopic Sequence 6 of 13.
Chromoendoscopy and magnifying endoscopy are useful for detection and recognition of small non polypoid lesions, for differential diagnosis between hyperplastic and adenomatous lesions and for determining not only the lateral extent but also the depth of a lesion. Pit analysis would especially be useful in the differential diagnosis between depressed-type early cancers (type IIIS) and flat adenomas with pseudodepression (type IIIL).
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Video Endoscopic Sequence7 of 13.
Another view using magnifying chromo-endoscopy.
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Video Endoscopic Sequence 8 of 13.
In order to establish the magnitude of the size of the polyp and to plan its extraction, we used forceps of biopsy, moving forwarding and pushing the adenoma. The adenoma was excised using a snare wire and electrocautery.
See the video clip.
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Video Endoscopic Sequence 9 of 13.
A polypectomy is being performed, the polypectomy snare is appreciated.
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Video Endoscopic Sequence 10 of 13.
Note the traction which the lesion is being removed.
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Video Endoscopic Sequence 11 of 13.
The fragment of the polyps have been falled out. Shown here after removal of the polyp.
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Video Endoscopic Sequence 12 of 13.
Benign tubulo villous neoplasia of the ileocecal valve with Mild dysplasia. Mild dysplasia is characterized by uniform loss of mucin and hyperchromatic and elongated cells. Glands appear branched and budding.
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Video Endoscopic Sequence 13 of 13.
Another Histopatologic view.
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Stalked polyp of the sigmoid.
The image and the video display several small polyps. Familiar polyposis of the colon (FPC).
More images and video clips about this case press here.
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Tubulo-Villous Adenoma.
Adenomatous polyps are, by definition, neoplastic. Although benign, they are the direct precursors of adenocarcinomas and follow a predictable cancerous temporal course unless interrupted by treatment. They can be either pedunculated or sessile. Adenomas are divided into 3 subtypes based on histologic criteria, (1) tubular, (2) tubulovillous, and (3) villous. According to World Health Organization (WHO) criteria, villous adenomas are composed of greater than 80% villous architecture. Tubular adenomas are encountered most frequently (80-86%). Tubulovillous adenomas are encountered less frequently (8-16%), and villous adenomas are encountered least frequently (5%).
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Video Endoscopic Sequence 1 of 3.
Enormous Sessile Villous Adenoma.
An 80 year-old female have a sessile mass between the first and second rectal valves. Morphologically, villous adenomas of the colon are generally sessile and papilliferous. Lesions that tend to secrete mucus. The epithelial element of these adenomas is more dysplastic than that seen in tubular adenomas and consequently these have, in general, greater potential for malignant change.
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Video Endoscopic Sequence 2 of 3.
The immediate risks of adenomas include hemorrhage, obstruction with intussusception, and, possibly, torsion. However, the main concern is malignant progression of the villous adenoma. Studies have defined the risk of progression of adenomas to adenocarcinoma.
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Video Endoscopic Sequence 3 of 3.
Villous Adenoma, after spraying methilene blue.
Adenomas are believed to have an abnormal process of cell proliferation and apoptosis. The proliferative component is not confined to the crypt base and accumulates onto the surface and infolds downward. In villous adenomas, mesenchymal proliferation results in longer projections and larger polyps. Epidemiological studies provide evidence of adenoma-to-carcinoma progression. The mean age of adenoma diagnosis is 10 years earlier than with carcinoma, and progression to carcinoma takes a minimum of 4 years.
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Video Endoscopic Sequence 1 of 7.
Cap polyposis that resemble a adenocarcinoma of the rectum.
This 22 year-old lady, has been presented with rectal bleeding and mucus discharge, also has been suffering of Bulimia Nervosa.
Digital rectal examinations revealed polypoidal masses in the rectum.
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Video Endoscopic Sequence 2 of 7.
Cap polyposis is characterized by the presence of inflammatory polyps with a "cap" of granulation tissue. It may represent one end of a spectrum of conditions caused by chronic straining.
Polyps have an erythematous and inflamed appearance and are capped with a purulent fibrin exudate.
The pathogenesis is not well known although many affected individuals have long standing colonic dysmotility manifested by chronic constipation. It is hypothesized that recurrent mucosal trauma due to chronic straining can result in the clinical spectrum of mucosal prolapse syndrome which includes solitary rectal ulcer syndrome and the more dramatic finding of cap polyposis.
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Video Endoscopic Sequence 3 of 7.
The findings here are of cap polyposis, a rare condition thought to be related to chronic constipation and straining causing prolapse of mucosa in the rectum and sigmoid. Often mistaken for pseudopolyps, the polyps seen can range from sessile to pedunculated in morphology and can be found anywhere from the rectum to the cecum although the vast majority are found in the rectosigmoid region as in this example.
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Video Endoscopic Sequence 4 of 7.
Chromoendoscopy with indigo carmin.
Cap polyposis is characterized by rectosigmoid polyps that have tortuous elongated crypts and are covered by a cap of fibropurulent exudate. The pathogenesis is unknown, but the histology suggests that mucosal prolapse may play a role. The current therapy often used for inflammatory bowel diseases has frequently been ineffective. Overall, infliximab lead to symptomatic improvement and histologic resolution of the polyps.
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Video Endoscopic Sequence 5 of 7.
Argon Plasma Coagulation was used as ablative therapy.
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Video Endoscopic Sequence 6 of 7.
Recently, there was a case report published, on a patient with cap polyposis who was treated with a single infusion of infliximab 5 mg/kg and who demonstrated dramatic symptomatic improvement.
Medline.
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Video Endoscopic Sequence 7 of 7.
Status after the polyps were considered successfully ablated with argon plasma coagulation.
Three different session of argon plasma coagulator were used.
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Cap Polyposis.
Another Case.
This 47 year-old female, who has been suffering of rectal discharge with mucoid secretion.
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Video Endoscopic Sequence 1 of 3.
Flat Adenoma of the third rectal valve, with irregular surface is appreciated.
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Video Endoscopic Sequence 2 of 3.
High magnification with Cresyl violet.
Dye spray technique may result in a higher detection rate of flat colonic lesions. Clinical usefulness of high-resolution chromoendoscopy, i.e. colonoscopy with topically applied agents, in an attempt to discriminate neoplastic from non-neoplastic colorectal polyps. Using both specially designed videocolonoscopes that produce high-resolution images at great magnification and dye spray, a contrast stain which accentuates epithelial topography, thus allowing recognition of otherwise unnoticeable epithelial changes, it seems possible to distinguish adenomatous from nonadenomatous colorectal polyps measuring <10 mm3. The clinical utility of standard videocolonoscopy and staining with a dye especially in the diagnosis of very small colorectal polyps.
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Video Endoscopic Sequence 3 of 3.
High-resolution video colonoscopy and chromoscopy.
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Tubular Adenoma.
Of the third rectal valve some diverticulae are observed nearby.
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Most colonic polyps are asymptomatics. Adenomoatous Polyps result of epithelial and dysplasia. Tree types: tubular, villous and mixed. Risk of malignancy related to size, histologic type and severity of dysplasia. Since they are considered premalignant all should be removed.
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Video Endoscopic Sequence 1 of 2.
Large and long stalk villous adenoma inserting in the rectal dentate line, appearing as a multi lobular mass.
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Polyps are classified based on the type of tissue they contain:
Tubular adenomas are the most common type. About 80% to 86% of adenomatous polyps are this type. Tubular adenomas are the polyps that are least likely to develop into colon cancer.
Villous adenomas are the least common type. About 3% to 16% of adenomatous polyps are this type. Villous adenomas are most likely to become cancerous.
Tubulovillous adenomas are a combination of the other two tissue types. About 8% to 16% of adenomatous polyps are this type and are more likely than tubular but less likely than villous adenomas to develop into cancer.
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Video Endoscopic Sequence 2 of 2.
Prolapsing tumor through the anus.
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Pediculated tubular adenoma.
Colonoscopic picture of a pediculated tubular adenoma. Note the stalk and raspberry-like appearance of the polyp. Most adenomas are encountered incidentally during colorectal cancer surveillance.
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Large Villous Adenoma of the Sigmoid.
The cancer risk of a tubular adenoma is controversial, but strong evidence suggests that it can become malignant. Risk of malignancy is related to size; a 1.5-cm tubular adenoma has a 2% risk. As its size increases, its glands become villous. When > 50% of its glands are villous, it is called a villoglandular polyp; its malignancy potential is still that of a tubular adenoma. When > 80 % of the glands are villous, the polyp is called a villous adenoma , which becomes malignant in about 35% of cases. A villous adenoma has a greater risk of malignancy than a tubular adenoma of the same size.
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Video Endoscopic Sequence 1 of 2.
Cecum stalk polyp inside of the appendiceal orifice.
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Video Endoscopic Sequence 2 of 2.
The appendiceal orifice is appreciated after the biopsies of the polyp. The diameter of the orifice is enlarged and almost permitted introduction of the tip of the colonoscope.
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Flat ulcerated tubular adenoma.
Flat ulcerated tubular adenoma in the ascending colon that caused severe hemorrhage and hypovolemic shock.
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Serrated large Mass.
A 32 year-old physician, who had rectal bleeding. A large mass between the second and third rectal valve is appreciated. The histopathologic study reveled tubular adenoma.
The "hyperplastic polyp" is considered a benign lesion with no malignant potential, whereas "serrated adenoma" is a precursor of adenocarcinoma. The morphologic complexity of the serrated adenoma varies from being clearly adenomatous to being difficult to distinguish from hyperplastic polyp, which creates a need for more detailed morphologic analysis of all serrated polyps.
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Large ulcerated polyp at the splecnic flexure.
A 71 year-old male that had severe rectal bleeding and shock due to this tumor.
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Video Endoscopic Sequence 1 of 2.
Bilobulated, Pediculated Villotubular Adenoma.
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Video Endoscopic Sequence 2 of 2.
A large stalk is seen.
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Lymphoid hyperplasia.
Seen at hepatic angle, multiple tiny 1 to 2 mm in size usually incidental.
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Video Endoscopic Sequence 1 of 2.
Enormous tubulovillous tumor of the sigmoid with wide pediculated stalk.
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Video Endoscopic Sequence 2 of 2.
Another view of the wide stalk with the mass.
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Video Endoscopic Sequence 1 of 2.
Juvenile polyps in a 15 year-old girl. She presented rectal hemorrhage for a week. The image displays a bleeding juvenile polyp. The video displays two rectal polyps.
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Video Endoscopic Sequence 2 of 2.
Endoscopic Polypectomy of a rectal juvenile polyp.
More cases of Polypectomy see Polypectomy and Juvenile Polyposis. More polyps should see Familiar polyposis.
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