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Duodenum.
The video clip displays second and third portion.
The duodenum, into which the stomach opens, is about 25 cm long, C-shaped and begins at the pyloric sphincter. It is almost entirely retroperitoneal and is the most fixed part of the small intestine.
For more endoscopic details download the video clips by clicking on the endoscopic images, wait to be downloaded complete then press Alt and Enter; thus you can observe the video in full screen.
All endoscopic images shown in this Atlas contain video clips.
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Video Endoscopy with Magnifying.
Duodenum the intestinal villis are observed.
The gastrointestinal tract is considered one of the largest immune organs of the body. Disruption of bowel mucosa not only compromises digestive and absorptive functions, but also vital immune functions.
Gut-associated lymphatic tissue (GALT) confers specific immunity in the form of secretory immunoglobulin-A (sIgA) while specialized cells in the mucosa, such as macrophages, natural killer cells, mast cells and intraepithelial lymphocytes, protect against absorption of intestinal toxins and pathogens. Non-specific immunity is conferred by gastric acidity, mucus, motility, digestive enzymes and normal bacterial flora. Chronic permeability defects and associated mucosal damage may therefore lead to considerable compromise of immune function.
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Magnifying Endoscopy.
Magnifying Duodenoscopy of the duodenal bulb, the intestinal villis are observed.
To know the more detailed findings of the small intestinal mucosa with the use of a magnifying endoscope.
Most cells formed from the undifferentiated columnar cell at the base of the crypt, migrate along the sides of the villi up to the tip of the villi where they are sloughed off. As they migrate they differentiate into the absorptive columnar cell or the goblet cell. This is a continuous process whereby the cells of the epithelium are replaced every 3 days. The rapidly replicating undifferentiated columnar cells are almost continually undergoing mitosis which makes them especially sensitive to the effects of radiation therapy, cancer chemotherapy and various toxins and enzymes of microbial cells. When their reproduction is interrupted, the other cells of the epithelium continue to migrate and slough off. This disrupts the epithelium which causes 3 major effects: compromization of the first line of microbial defense, malabsorption and diarrhea.
The intestine absorbs both exogenous fluids and its own secretions. The secretions of the intestine and digestive glands are so great that, were they not resorbed, death from dehydration would result in 24 hours.
Medline.
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Magnifying Duodenoscopy.
Magnifying Duodenoscopy of the duodenal bulb. The intestinal villis are observed.
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Papilla of Vater.
A normal papilla Vater, this picture was taken through a forward-viewing gastroscope.
Vater, Abraham (1684-1751), German anatomist. Vater was a professor of anatomy and botany and later of pathology and therapeutics at Wittenberg. In 1710 he first noted the ampulla that has been named after him, but he did not publish a description of it until 1720. In 1717 he described the terminal capsules of certain sensory nerve fibers. They were later described by the Italian anatomist Filippo Pacini in 1840. Now these corpuscles are more commonly identified with Pacini than with Vater.
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Video Endoscopic Sequence 1 of 2.
Vaterīs papilla major and minor.
The main papilla of Vater is a small nipple-like structure on the wall of the duodenum, in its "second part." The papilla forms the main exit hole for the bile and pancreatic juices which flow down the bile duct and pancreatic duct. Rarely there are two separate holes close together within the same papillary nipple. The papilla remains closed at rest, because of the activity of a muscular valve (sphincter). The sphincter (of Oddi, another Italian) surrounds the exit of the bile duct and pancreatic duct. It opens by reflex action when foods enter the stomach, so that juices can be released to help in their digestion.
In most people there is a second smaller (minor, or accessory) papilla, situated about 2 cm (3/4 inch) above the main papilla, and slightly to its right. This is the exit hole for Santorini's duct. The minor papilla acts as a useful safety valve when the main papilla is not able to function correctly, but becomes the main site of drainage for pancreatic juices in the rare congential disease of pancreas divisum.
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Video Endoscopic Sequence 2 of 2.
In the video clip you can see the papilla major being retracting and become hidden in a duodenal diverticula.
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Video Endoscopic Sequence 1 of 3.
Emerging Bilis from the papilla.
In this endoscopic sequence of video clips you can appeciate the bilis that emerged from the papilla.
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Video Endoscopic Sequence 2 of 3.
Emeging Bilis from the papilla.
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Video Endoscopic Sequence 3 of 3.
Emerging bilis from the papilla.
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A normal appearing papilla.
A normal papilla Vater seen to the left in these pictures and video clips are taken through a forward-viewing endoscope.
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Ampulla of Vater.
The main papilla of Vater (named after an Italian) is a small nipple-like structure on the wall of the duodenum, in its "second part." The duodenum is the upper part of the small intestine, into which food flows from the stomach. The papilla forms the main exit hole for the bile and pancreatic juices which flow down the bile duct and pancreatic duct. Rarely there are two separate holes close together within the same papillary nipple. The papilla remains closed at rest, because of the activity of a muscular valve (sphincter). The sphincter (of Oddi, another Italian) surrounds the exit of the bile duct and pancreatic duct. It opens by reflex action when foods enter the stomach, so that juices can be released to help in their digestion. In most people there is a second smaller (minor, or accessory) papilla, situated about 2 cm (3/4 inch) above the main papilla, and slightly to its right. This is the exit hole for Santorini's duct. The minor papilla acts as a useful safety valve when the main papilla is not able to function correctly, but becomes the main site of drainage for pancreatic juices in the rare congential disease of pancreas divisum.
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Duodenal bulb seen in retroflexed maneuver.
The pylorus is seen. Adult endoscope was used. The video clip shows the endoscope pass from the bulb to the antrum.
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Duodenum in retroflexed maneuver.
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Papilla of Vater.
With frenulum and prominent plica longitudinalis.
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Papilla of Vater.
The papilla of Vatter is found at the medial aspect at the midpoint of the c loop. The papilla is bordered by the plica longitudinalis from the above and by another longitudinal fold, the frenulum, from below. The plica longitudinalis corresponds to the intraduodenal portion of the common bile duct, it windens as it approaches the papilla and ends in a bulging transverse fold. The preputium, which occasionally covers the papilla itself. The shape of the papilla may be hemispheric, papillary, or flat. It not only varies from patient to patient but its appearance may change somewhat during the examination.
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